However, Windows will search for USB port drivers and automatically it will install the drivers and your USB will again start working as usual.
Right-click on the USB Port and then select ‘ Uninstall‘ Under the Device Manager, expand the ‘Universal Serial Bus Controllers’ If you are worried about the security of your computer, you can uninstall the USB Mass Storage Drivers. Well, this is not the most recommended method, but still, it’s a helpful one. By Uninstalling your USB Mass Storage Drivers Don’t forget to enable that device later even after rebooting your computer. If the port was not working, then restart your computer. Step 4. Under Universal Serial Bus Controllers, select all the devices and with right-click Disable all and see if it is working or not. Step 3. Now you need to find Universal Serial Bus Controllers
On the left pane, click on the ‘Device Manager’ option. Then you will see a pop-up with windows similar to the above image. You need to Right Click on the My Computer/This PC icon and then select “Manage” However, if the above one failed, you can use this method to disable the USB ports through the Device Manager. The above method is the perfect way to disable USB ports on computers. This is how you can use the Windows registry to unblock/block USB ports in Windows 10. In that, to Disable, just change the Value data with “ 4” or for Next time if you want to Enable your USB port again then Change it to “ 3” but remember after every task or changing the value Close your Registry Editor. Now you have just to find out START in the working area. HIKEY_LOCAL_MACHINE -> SYSTEM -> CURRENT CONTROL SET -> SERVICES -> USBSTOR